Siemens announces first U.S. deployment of new lab process control system

BIND Biosciences launches first implementation phase as it develops new nanoparticle drug delivery platforms. Goal is shorter time to market. Link to related resources.


Atlanta, GA – One of the drivers of the pharmaceutical industry is having an effective pipeline of new product developments. Since new products can be patented and sold on an exclusive basis, manufacturers want to shorten the time to market as much as regulations will permit. Siemens has created an extensionof its Simatic PCS 7 process control platform called PCS 7 Lab which is designed to help capture intellectual property developed in the lab so that it can be used again when a product is ready for scale-up with larger manufacturing batches.

Siemens announced that BIND Biosciences Inc., of Cambridge, MA, is the first user in the U.S. that has selected the PCS 7 Lab platform to help its scientists manage pre- and post-clinical experimental data.

BIND Biosciences develops targeted therapeutics based upon its novel polymeric nanoparticle drug delivery technology platform. The drug itself is encased in a nano-container that is designed to seek out and attach itself to specific types of cells, such as a tumor. That way the therapeutic agent can be delivered exactly where it is needed. This technology concentrates the drug at the intended site of action while minimizing systemic exposure, improving efficacy and reducing off-target effects.

“The flexibility and expandability of the PCS 7 Lab system will allow us to grow economically and efficiently through all three phases of the implementation,” says Jeff Hrkach, BIND Biosciences vice president of pharmaceutical sciences. “The system has all the tools we need to collect and manage our data as well as protect our intellectual property.”

The PCS 7 Lab configuration, designed for laboratory and process development research and development applications, is based on Siemens’ Simatic PCS 7 Box. The UL-certified system includes a preinstalled rack of I/O modules that can be easily reconfigured to fit any size or type of laboratory environment.

"This partnership gives Siemens the opportunity to help BIND bring drugs to market faster," says Glenn Restivo, Siemens life sciences industry manager. “We adhere to the design of experiment and quality by design philosophies that build quality into every step of the process– from laboratory experimentation through every phase of manufacturing.”

BIND’s implementation of the PCS 7 project is underway and focuses on basic experimentation and data collection. A second phase is under consideration for cataloging and organizing experimental data. Phase three, also under consideration, will include Siemens’ Sipat for process analytical technology (PAT), Interspec for specification management and the R&D Suite for electronic lab notebook (ELN).

Also read:
- OPC Foundation releases draft ADI specification, aims to improve analyzer integration ; and

- A pproach for measuring economic benefit of process analytical technologies (PAT) .

Edited by Peter Welander, process industries editor
Control Engineering News Desk
Register here to select your choice of free eNewsletters .

No comments
The Top Plant program honors outstanding manufacturing facilities in North America. View the 2013 Top Plant.
The Product of the Year program recognizes products newly released in the manufacturing industries.
The Engineering Leaders Under 40 program identifies and gives recognition to young engineers who...
A cool solution: Collaboration, chemistry leads to foundry coat product development; See the 2015 Product of the Year Finalists
Raising the standard: What's new with NFPA 70E; A global view of manufacturing; Maintenance data; Fit bearings properly
Sister act: Building on their father's legacy, a new generation moves Bales Metal Surface Solutions forward; Meet the 2015 Engineering Leaders Under 40
Cyber security cost-efficient for industrial control systems; Extracting full value from operational data; Managing cyber security risks
Drilling for Big Data: Managing the flow of information; Big data drilldown series: Challenge and opportunity; OT to IT: Creating a circle of improvement; Industry loses best workers, again
Pipeline vulnerabilities? Securing hydrocarbon transit; Predictive analytics hit the mainstream; Dirty pipelines decrease flow, production—pig your line; Ensuring pipeline physical and cyber security
Upgrading secondary control systems; Keeping enclosures conditioned; Diagnostics increase equipment uptime; Mechatronics simplifies machine design
Designing positive-energy buildings; Ensuring power quality; Complying with NFPA 110; Minimizing arc flash hazards
Building high availability into industrial computers; Of key metrics and myth busting; The truth about five common VFD myths

Annual Salary Survey

After almost a decade of uncertainty, the confidence of plant floor managers is soaring. Even with a number of challenges and while implementing new technologies, there is a renewed sense of optimism among plant managers about their business and their future.

The respondents to the 2014 Plant Engineering Salary Survey come from throughout the U.S. and serve a variety of industries, but they are uniform in their optimism about manufacturing. This year’s survey found 79% consider manufacturing a secure career. That’s up from 75% in 2013 and significantly higher than the 63% figure when Plant Engineering first started asking that question a decade ago.

Read more: 2014 Salary Survey: Confidence rises amid the challenges

Maintenance and reliability tips and best practices from the maintenance and reliability coaches at Allied Reliability Group.
The One Voice for Manufacturing blog reports on federal public policy issues impacting the manufacturing sector. One Voice is a joint effort by the National Tooling and Machining...
The Society for Maintenance and Reliability Professionals an organization devoted...
Join this ongoing discussion of machine guarding topics, including solutions assessments, regulatory compliance, gap analysis...
IMS Research, recently acquired by IHS Inc., is a leading independent supplier of market research and consultancy to the global electronics industry.
Maintenance is not optional in manufacturing. It’s a profit center, driving productivity and uptime while reducing overall repair costs.
The Lachance on CMMS blog is about current maintenance topics. Blogger Paul Lachance is president and chief technology officer for Smartware Group.